The lab notebook
organic chemists deserve
Plan reactions, screen conditions, track substrate scope, and export publication-ready SI — all in one desktop app.
Windows & macOS · No account required · Your data stays local
Everything you need, nothing you don't
Reaction Setup
Add reagents with PubChem lookup, draw structures with Ketcher, auto-calculate equivalents and masses.
Methodology Screening
Compare conditions side-by-side in a spreadsheet-like table. Track yields, selectivity, and find optimal conditions.
Substrate Scope & SI Export
Record full characterization data and export publication-ready SI text or Word documents with proper formatting.
AI Assistant
Built-in AI chat with Claude, Ollama, Google AI, or OpenAI. Plan experiments by voice or text.
Markdown Notebook
Obsidian-compatible notes with [[links]], #tags, templates, and daily journal. Your notes, your files.
Mobile Access
Access your experiments from any phone or tablet on the same network. No cloud required.
Spectra & NMR Import
Import NMR data from MNova, view JCAMP spectra interactively, record IR/HRMS/GC-MS.
Local & Private
All data stored locally on your computer. No account, no cloud, no subscription required for basic use.
5 Languages
Traditional Chinese, English, Japanese, German, and French. With 5 beautiful themes.
4 experiment types
Each designed for a specific organic chemistry workflow
General Synthesis
Single-reaction experiments with full reagent setup, procedure steps, and results tracking.
Methodology Screening
Multi-condition optimization table. Compare catalysts, ligands, solvents, temperatures side-by-side.
PROMultistep Synthesis
Plan and record multi-step routes. Products carry over between steps automatically.
PROSubstrate Scope
Full characterization with NMR, IR, HRMS, HPLC. Export SI text and Word documents.
PROStart recording experiments today
Free forever for single-step synthesis. Upgrade when you're ready to publish.
Download Synvala